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Download scientific diagram | Case 1, 63-year-old male, sustained a snake bite injury with cytotoxic venom effect to left non-dominant hand. As a direct result, the patient suffered deep and superficial venous thrombosis in that limb and tissue necrosis of the skin over the dorsum of the hand. a shows loss of soft tissues overlying the common extensor tendons to the middle and ring fingers and the dorsal extensor expansion overlying the proximal interphalangeal joint and the proximal phalanx of the little finger before commencing PRP injections, at 2 weeks after two debridements. The patient received injections twice a week. A polyurethane semi-occlusive dressing covered the wound. The hand underwent splinting in a functional position, and a mobilization program included both passive and active movements between periods of rest. b shows a shrinking wound and granulating tendon 2 weeks after commencing injections. c shows granulated and epithelialized tendons, with further wound shrinkage, at 5 weeks after commencing injections. d shows a healed hand at 80 days after therapy commencement, having taken 44 days for granulation tissue to cover the bare tendons. The hand demonstrated minimal area of scarring relative to the original size of the wound defect from publication: Intra-tendinous platelet rich plasma injection therapy for healing wounds with exposed tendons: a clinical case series | Background Platelets are rich in cytokines and growth factors. Exposed tendons in wounds do not naturally heal by granulation and epithelization. The study aimed to explore the effects of PRP injection therapy on exposed tendons in open wounds and determine if the tendon | Tendons, Platelet Rich Plasma and Artificial Skin | ResearchGate, the professional network for scientists.
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